Mechanics of allostery: contrasting the induced fit and population shift scenarios
R. Ravasio, S. M. Flatt, L. Yan, S. Zamuner, C. Brito, M. Wyart
The paper investigates allosteric conformational changes in proteins, finding that a soft elastic mode with high shear is common, and that cooperativity depends on stiffness and protein size.
bioRxiv · Jun 18, 2019Biophysics