Synchronous chromosome segregation in mouse oocytes is ensured by biphasic securin destruction and cyclin B1-Cdk1
C. Thomas, M. D. Levasseur, R. J. Harris, O. R. Davies, S. Madgwick
This study identifies a novel mechanism in mouse oocytes that ensures synchronous chromosome segregation through biphasic securin destruction and cyclin B1-Cdk1 inhibition of separase.
bioRxiv · Oct 30, 2019 · PreprintCell Biology