Predicting the Functional Impact of KCNQ1 Variants with Artificial Neural Networks
S. Phul, G. Kuenze, C. G. Vanoye, C. R. Sanders, A. L. George, J. Meiler
This paper develops ANN models to predict the functional impact of KCNQ1 variants using biophysical features, outperforming models based solely on evolutionary features.
bioRxiv · Dec 6, 2021Biophysics