Author

S. Piatt

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Biophysics· 2

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Approach:experimental assay· 1 Approach:statistical model· 1

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A. C. Price· 2 shared J. Loparo· 1 shared

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2018-2018 · peak 2/yr

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2 shared papersBiophysics

A. C. Price

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2 papers

Recent·Most cited

The sequence dependent search mechanism of EcoRI

A. C. Price, J. Loparo, S. Piatt

This study investigates how EcoRI searches DNA using single-molecule observations, revealing a combination of sliding and hopping at different salt concentrations and a model involving hemi-specific binding.

bioRxiv · Oct 15, 2018 · PreprintBiophysics

ANALYZING DWELL TIMES WITH THE GENERALIZED METHOD OF MOMENTS

S. Piatt, A. C. Price

This paper applies the Generalized Method of Moments (GMM) to estimate kinetic parameters from single molecule dwell time data, showing it performs comparably to nonlinear least-squares minimization with benefits in small sample sizes and fast decay time identification.

bioRxiv · May 9, 2018Biophysics