T cells modulate the microglial response to brain ischemia
C. Benakis, A. Simats, S. Tritschler, S. Heindl, S. Besson-Girard, G. Llovera, K. Pinkham, A. Kolz, F. J. Theis, O. Gökce, A. Peters, A. Liesz
This study shows engineered T cells overexpressing IL-10 alter microglial gene expression to a pro-regenerative profile after stroke, highlighting T cell-microglia interactions in neuroinflammation.
bioRxiv · Sep 23, 2021Immunology