Author

S. Tyekucheva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Assay:protein structure· 1

Frequent Co-Authors

M. Loda· 2 shared D. F. Sanchez· 1 shared E. L. Imada· 1 shared E. M. Ebot· 1 shared E. M. Schaeffer· 1 shared G. Parmigiani· 1 shared G. R. Franco· 1 shared J. B. Vaselkiv· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPathology

M. Loda

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Author profile →

2 papers

Recent·Most cited

Extent, impact, and mitigation of batch effects in tumor biomarker studies using tissue microarrays

K. H. Stopsack, S. Tyekucheva, M. Wang, T. A. Gerke, J. B. Vaselkiv, K. L. Penney, P. W. Kantoff, S. P. Finn, M. Fiorentino, M. Loda, T. L. Lotan, G. Parmigiani, L. A. Mucci

This study assesses batch effects in TMA-based cancer biomarker studies and shows mitigation methods reduce variance and alter clinical associations.

bioRxiv · Jun 29, 2021Pathology

Transcriptional landscape of PTEN loss in primary prostate cancer

E. L. Imada, D. F. Sanchez, W. Dinalankara, T. Vidotto, E. M. Ebot, S. Tyekucheva, G. R. Franco, L. Mucci, M. Loda, E. M. Schaeffer, T. Lotan, L. Marchionni

The paper identifies a transcriptomic signature of PTEN loss in prostate cancer, revealing immune system activation and cell-cycle gene upregulation, and expands it to include non-coding RNAs.

bioRxiv · Oct 8, 2020 · PreprintCancer Biology