Intravital Deep-Tumor Single-Beam 2-, 3- and 4-Photon Microscopy
G.-J. Bakker, S. Weischer, J. Heidelin, V. Andresen, M. Beutler, P. Friedl
This paper demonstrates that high-pulse-energy low-duty-cycle infrared excitation enables deeper tissue penetration in tumors and bone compared to conventional 2-photon excitation, allowing simultaneous multi-parameter imaging.
bioRxiv · Sep 29, 2020Cancer Biology