Author

S. Wonnacott

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Biochemistry· 1

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. J. Mulholland· 1 shared A. S. F. Oliveira· 1 shared G. Ciccotti· 1 shared I. Bermudez· 1 shared R. B. Sessions· 1 shared T. Gallagher· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

A. J. Mulholland

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1 paper

Recent·Most cited

Structural and temporal basis for agonism in the α4β2 nicotinic acetylcholine receptor

A. S. F. Oliveira, I. Bermudez, T. Gallagher, S. Wonnacott, G. Ciccotti, R. B. Sessions, A. J. Mulholland

This study uses molecular dynamics simulations to analyze how full and partial agonists induce different conformational changes in the α4β2 nicotinic acetylcholine receptor, affecting signal propagation.

bioRxiv · Feb 23, 2022 · PreprintBiochemistry