Author

S. Y. Ow

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. D. Nash· 1 shared A. Quek· 1 shared C. Panousis· 1 shared E. Kapp· 1 shared I. Drulyte· 1 shared M. J. Wilson· 1 shared M. Pelzing· 1 shared R. Ghai· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

A. D. Nash

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1 paper

Recent·Most cited

Structural basis for inhibition of βFXIIa by garadacimab

I. Drulyte, R. Ghai, S. Y. Ow, E. Kapp, A. Quek, C. Panousis, M. J. Wilson, A. D. Nash, M. Pelzing

This paper presents a high-resolution cryo-EM structure of garadacimab Fab bound to βFXIIa, revealing its unique binding mechanism and insights into FXII inhibition in HAE.

Structure · Oct 1, 2024Peer-reviewedBiochemistry