With No Lysine Kinase 1 Promotes Right Ventricular Dysfunction Via Glucotoxicity
S. Z. Prisco, M. Eklund, T. Thenappan, K. W. Prins
This study shows that WNK1 inhibition with WNK463 reduces glucotoxicity, improves mitochondrial/peroxisomal function, and enhances right ventricular function in pulmonary arterial hypertension.
bioRxiv · Jun 22, 2021Physiology