Investigating the efficacy of triple artemisinin-based combination therapies (TACTs) for treating Plasmodium falciparum malaria patients using mathematical modelling
J. A. Simpson, J. McCaw, P. Cao, F. J.I. Fowkes, S. Zaloumis, R. N. Price, S. Dini
This paper uses mathematical modeling to evaluate the efficacy of triple artemisinin-based combination therapy (TACT) against Plasmodium falciparum malaria, showing that adding mefloquine improves parasitological outcomes despite drug resistance.
bioRxiv · May 27, 2018Pharmacology & Toxicology