Polyelectrolyte domains in intrinsically disordered regions differentially regulate intracellular biomolecular condensation
Yoonjeong Choi, Yujin Lee, S.D. Cho, Yanyan Pan, Yemuk Kang, Chan‐Gi Pack, Youngtae Jeong, Kiwon Song
This study identifies charged amino acid clusters in intrinsically disordered regions that regulate intracellular condensation in yeast and disease-associated proteins.
bioRxiv · Sep 9, 2025 · PreprintCell Biology