Functional memory T cells are derived from exhausted clones and expanded by checkpoint blockade
Colin J. Raposo, Patrick Yan, Andy Y. Chen, Saba Majidi, Kamir J. Hiam-Galvez, Ansuman T. Satpathy
This study shows that exhausted T cells can form functional memory T cells after antigen clearance, and checkpoint blockade expands these memory clones.
bioRxiv · Feb 10, 2025 · PreprintImmunology