Generative and integrative modeling for transcriptomics with formalin fixed paraffin embedded material
Eliseos J. Mucaki, Wenhan Zhang, A Saha, Sabina Trebinjac, Sharon Nofech‐Mozes, E Rakovitch, Vanessa Dumeaux, Michael T. Hallett
The paper introduces PREFFECT, a probabilistic framework to improve analysis of FFPE-derived RNA-seq data by addressing transcript dropout and variance through generative models and graph attention mechanisms.
Journal of Translational Medicine · Sep 30, 2025Peer-reviewedBioinformatics