Rapid TetOn-mediated gene expression in neuronsacross the lifespan using uTTOP
Christopher K. Salmon, Gaël Quesseveur, Gee Hung Leo Cheong, Sabrina Chierzi, Miranda Green, Michael P. Rosen, Andy Y. L. Gao, J. Benjamin Kacerovsky, Keith Kazuo Murai
This study introduces uTTOP, a method for rapid and temporally precise gene expression in neurons across the mouse lifespan, showing it can induce expression in multiple brain regions with faster kinetics than existing methods.
bioRxiv · Dec 5, 2023 · PreprintNeuroscience