Fever-range temperature enhances B cells in vitro but is dispensable for the germinal center in vivo
Sofiane Mohammed, Zineb Sbihi, Patrick Laignel, Ines Houtia, Sabrina Haddou, Emanuele Procopio, Océane Morales, Grégory Franck, Giuseppina Caligiuri, Antonino Nicoletti, Marie Le Borgne
This study shows fever-range temperature enhances B cell function in vitro but does not improve germinal center responses or antibody production in vivo.
bioRxiv · Oct 13, 2026 · PreprintImmunology