Engineering developmental transitions during human neurulation through modular integration of multimodal spatial cues
Masaya HAGIWARA, Sae Nozaki, Yosuke SUGINO, Yen Xuan Ngo, Laura Yuriko González-Teshima, Isao Matsuo
This paper introduces MoSAIC, a platform that integrates spatial cues to guide human neurulation in vitro, enabling the study of developmental transitions through controlled mechanical and chemical perturbations.
bioRxiv · Oct 7, 2026 · PreprintBioengineering