L-selectin shedding regulates functional recovery and neutrophil clearance following spinal cord injury in a sex-dependent manner
Miranda E. Leal-Garcia, Mia R. Pacheco, Shelby K. Reid, Victoria S. Tseng, Megan A. Kirchhoff, Sai Tadiboyina, David Min, Dylan A. McCreedy
This study shows that L-selectin shedding improves functional recovery and white matter sparing in female mice but not males after spinal cord injury, with sex-dependent effects on neutrophil clearance.
bioRxiv · May 28, 2025 · PreprintNeuroscience