A Novel Regulation on the Developmental Checkpoint Protein Sda that Controls Sporulation and Biofilm Formation in Bacillus subtilis
Yinghao He, Yuxuan Qin, Jennifer L. Greenwich, Samantha Balaban, Migue Van Louis Darcera, Kevin Gozzi, Yunrong Chai
The paper identifies a serine codon hierarchy that affects translation efficiency in Bacillus subtilis, showing that TCN codons cause ribosome pausing and regulate gene expression, including the sda gene involved in sporulation and biofilm formation.
Journal of Bacteriology · Feb 11, 2025Peer-reviewedGenetics