The role of the NLRP3 inflammasome in a CLN2 mouse model of neuroinflammation
Kathryn Sanchez, Samantha Elizalde, Nancy B. Schwartz, Miriam S. Domowicz
This study investigates the role of the NLRP3 inflammasome in a CLN2 mouse model, showing that inflammasome activation occurs at 3 months and that its inhibition reduces neuroinflammation.
bioRxiv · Oct 14, 2026 · PreprintCell Biology