Bespoke single cell molecular and tissue-scale analysis reveals mechanisms underpinning development and disease in complex developing cell populations
Magdalena E Strauß, Mai-Linh Nu Ton, Samantha Mason, Jaana Bagri, Luke T. G. Harland, Iván Imaz-Rosshandler, Nicola K. Wilson, Jennifer Nichols, Richard C. V. Tyser, Berthold Göttgens, John C. Marioni, Carolina Guibentif
The paper develops statistical tools to analyze gene knockouts in mouse embryos and applies them to study developmental disruptions and cancer therapy responses.
bioRxiv · Oct 11, 2023 · PreprintGenomics