Reversal of neuronal tau pathology, metabolic dysfunction, and electrophysiological defects via adiponectin pathway dependent AMPK activation.
Eric R. McGregor, Danny J. Lasky, Olivia J. Rippentrop, Josef P. Clark, Samantha Wright, Mathew V. Jones, Rozalyn M. Anderson
This study shows that activating the adiponectin receptor with AdipoRon reduces tau pathology, metabolic dysfunction, and electrophysiological defects by targeting mitochondrial function and related pathways.
Communications Biology · Jan 4, 2025Peer-reviewedNeuroscience