Successful gene editing in tetraploid alfalfa using the open-source, AI-derived OpenCRISPR-1
Sameena Alam, Udaya Subedi, Kimberley Burton Hughes, Guanqun Chen, Letitia M. Da Ros, Andriy Bilichak, Stacy D. Singer
This study shows OpenCRISPR-1, an AI-derived Cas enzyme, successfully edits genes in tetraploid alfalfa with mono- or bi-allelic editing in 30% of genotypes.
Canadian Journal of Plant Science · Jan 1, 2026Peer-reviewedPlant Biology