A macrophage-derived noncanonical WNT niche drives immune exclusion in pancreatic cancer
Na Hyun Kim, Young Min Song, San Sung Kwon, Sang Hyub Lee, Eun Na Kim, Jung Joo Hong, Seung Hyeok Seok, Yi Rang Na
This study identifies a macrophage-derived noncanonical WNT niche that drives immune exclusion in pancreatic cancer by inhibiting CD8 T cell proliferation.
bioRxiv · Feb 9, 2026 · PreprintCancer Biology