Effects of Inosine-5'-Monophosphate Dehydrogenase (IMPDH/GuaB) Inhibitors on Borrelia burgdorferi Growth in Standard and Modified Culture Conditions
Eric L. Siegel, Connor Rich, Sanchana Saravanan, Patrick Pearson, Guang Xu, Stephen M. Rich
This study shows that IMPDH inhibitors reduce Borrelia burgdorferi growth in modified culture conditions, with 6-Chloropurine riboside being more effective than mycophenolic acid.
Microorganisms · Oct 15, 2024Peer-reviewedMicrobiology