The Spread of Interferon-γ in Melanomas is Highly Spatially Confined, Driving Non-Genetic Variability in Tumor Cells
Edoardo Centofanti, Chad Wang, Sandhya Iyer, Oleg Krichevsky, Alon Oyler‐Yaniv, Jennifer E. Oyler
The paper studies the spatial spread of IFN-gamma in melanomas and finds it is confined, leading to non-genetic cellular variability and altered T cell susceptibility.
Proceedings of the National Academy of Sciences · Aug 21, 2023Peer-reviewedSystems Biology