Systems BiologyProceedings of the National Academy of SciencesPeer-reviewed
The Spread of Interferon-γ in Melanomas is Highly Spatially Confined, Driving Non-Genetic Variability in Tumor Cells
Edoardo Centofanti, Chad Wang, Sandhya Iyer…·Jennifer E. Oyler
The paper studies the spatial spread of IFN-gamma in melanomas and finds it is confined, leading to non-genetic cellular variability and altered T cell susceptibility.