Dynamic transcriptional remodeling in alcohol use disorder reveals immune dysregulation and adaptive shifts in coagulation during therapy
Susanne Edelmann, Thomas Hentrich, Sanya Esser, Sarah Pasche, Gilles Gasparoni, Mirac Nur Musaoğlu, Milan Zimmermann, Julia Schulze-Hentrich, Vanessa Nieratschker
The paper analyzes transcriptomic changes in peripheral blood of AUD patients during withdrawal therapy, finding partial normalization of gene expression but persistent immune and coagulation dysregulation.
bioRxiv · May 18, 2026 · PreprintMolecular Biology