Thomas Hentrich

MethylBench benchmarks DNA methylation profiling methods across sequencing platforms, finding consistent DMC hotspots and highlighting platform-specific strengths and limitations.

The paper analyzes transcriptomic changes in peripheral blood of AUD patients during withdrawal therapy, finding partial normalization of gene expression but persistent immune and coagulation dysregulation.

This study compares lipidomes of five yeast strains, finding significant differences in lipid classes and molecular species, with transcriptomic data suggesting post-transcriptional regulation.

The paper identifies indirect molecular links between early life adversity and adult social anxiety disorder through immune-related signal transduction pathways using transcriptome analysis.

This study analyzes genome and transcriptome data from discordant monozygotic twins with Mayer-Rokitansky-Kuster-Hauser syndrome to identify genetic and transcriptional differences.

The paper develops endometrial organoids from MRKH patients to study disease pathways and identifies dysregulated genes in reproductive tract development.

This study profiles endometrial tissue from MRKH syndrome patients using RNA-seq to identify altered transcription patterns and candidate genes involved in the syndrome.

This paper describes a novel Ataxin-3 knock-in mouse model that replicates key neuropathological, behavioral, and transcriptional features of human SCA3 disease.