Genome-wide association and multi-omic analyses reveal new mechanisms for Heart Failure
Marios Arvanitis, Emmanouil Tampakakis, Yanxiao Zhang, Wei Wang, Adam Auton, Michelle Agee, Stella W. Aslibekyan, Robert K. Bell, Katarzyna Bryc, Sarah Clark, Sarah L. Elson, Kipper Fletez‐Brant, Pierre Fontanillas, Nicholas A. Furlotte, Pooja Gandhi, , Alexis J. Battle
This study identifies one known and two novel genetic variants associated with heart failure through GWAS and multi-omic analyses, revealing potential causal mechanisms and shared heritability with musculoskeletal traits.
Nature Communications · Feb 28, 2020Peer-reviewedGenetic & Genomic Medicine