Emmanouil Tampakakis

The paper identifies a bimodal m6A code in cardiac development, showing how m6A stoichiometry and context regulate metabolic switches and gene expression.

This study shows that TAFAZZIN deficiency disrupts mitochondrial maturation in cardiomyocytes, leading to structural and functional impairments associated with Barth syndrome cardiomyopathy.

This study shows that sympathetic NPY is critical for metabolic and cardiovascular regulation in mice, affecting glucose homeostasis, cold tolerance, and heart rate.

The paper identifies cardiac progenitors as a source of Wnts that regulate second heart field development through secretion, using genetic manipulation and single-cell RNA sequencing in mice.

This study shows satellite glia are essential for sympathetic neuron survival, activity, and autonomic function in mice, with implications for cardiovascular disease and hypertension.

This study shows noncanonical Notch signaling has stage-specific roles in cardiac development, inhibiting early heart formation but promoting later growth.

This study identifies PGC1/PPAR signaling and its regulators Yap1 and SF3B2 as key drivers of cardiomyocyte maturation through single-cell transcriptomic analysis across neonatal to adult hearts.

This study identifies one known and two novel genetic variants associated with heart failure through GWAS and multi-omic analyses, revealing potential causal mechanisms and shared heritability with musculoskeletal traits.