Author

Sarah McKeown

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Organism:C. elegans· 1 Approach:machine learning (classical)· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Adam Saunders· 1 shared Chandler Bradford· 1 shared Christine G. KimiD· 1 shared Christopher E. HopkinsiD· 1 shared Ingo HelbigiD· 1 shared Jennifer A. Lawson· 1 shared Kathryn McCormick· 1 shared Kolt Mcbride· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Adam Saunders

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1 paper

Recent·Most cited

A Gene Replacement Humanization Platform for Rapid Functional Testing of Clinical Variants in Epilepsy-associated STXBP1.

Kathryn McCormick, Trisha Brock, Matthew Wood, Lan Ping Guo, Kolt Mcbride, Christine G. Kim, Lauren Resch, Stelian Pop, Chandler Bradford, Preston S. Kendrick, Jennifer A. Lawson, Adam Saunders, Sarah McKeown, Ingo Helbig, Matthew Neil Bainbridge, Christopher E. Hopkins

The paper uses C. elegans to functionally test STXBP1 variants, classifying them as benign, pathogenic, or VUS with machine learning models.

bioRxiv · Aug 13, 2021 · PreprintGenetics