HIV remodels germinal centers through T follicular helper cell loss
Derek R. Jacobs, Faiaz Abdool, Lily Pohlenz, Danielle Curtis, Raman Gill, John Peyton Bush, Michael Martin, Julia Toman, Warren Paul Kuhn, Sarena Maistry, Ashley Levy, Ronald S. Veazey, Meagan Watkins, Jay Rappaport, James Porterfield
This study shows HIV reduces T follicular helper cells and alters germinal center structure in people living with HIV, independent of CD4 count.
bioRxiv · Oct 10, 2026 · PreprintMicrobiology