A Modular Machine Learning Framework for Small-Molecule Drug Repurposing Based on Organ Permeability, Target Binding, and Biomarker Modulation
Harkirat Singh Arora, Saroj Dhakal, Yorgos M. Psarellis, Sriram Chandrasekaran, Panteleimon D. Mavroudis, Nikhil Pillai
SCOUT is a machine learning framework for drug repurposing that integrates organ permeability, target binding, and biomarker modulation to prioritize candidates with high therapeutic relevance.
bioRxiv · Apr 17, 2026 · PreprintSystems Biology