Machine learning directed organoid morphogenesis uncovers an excitable system driving human axial elongation
Giridhar M. Anand, Heitor C. Megale, Sean H. Murphy, Theresa Weis, Zuwan Lin, Yichun He, Xiao Wang, Jia Liu B, Sharad Ramanathan
This study uses machine learning to optimize organoid morphogenesis, revealing an excitable system driven by WNT and FGF signaling that governs human axial elongation.
Cell · Jan 18, 2023Peer-reviewedDevelopmental Biology