High levels of the cardiomyocyte-specific kinase Tnni3k impair zebrafish heart regeneration by driving chronic myocardial inflammation
Miriam Fernández-Lajarín, Sean Keeley, Juan Manuel González‐Rosa
This study shows that overexpression of TNNI3K in zebrafish impairs heart regeneration by causing chronic inflammation and fibrosis rather than cell-cycle defects.
bioRxiv · Sep 9, 2026 · PreprintDevelopmental Biology