Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits
Sung Chun, Sebastian Akle, Athanasios Teodosiadis, Brian E. Cade, Heming Wang, Tamar Sofer, Daniel S. Evans, Katie L. Stone, Sina A. Gharib, Sutapa Mukherjee, Lyle John Palmer, David R. Hillman, Jerome I. Rotter, Craig L. Hanis, John A. Stamatoyannopoulos, , Shamil R. Sunyaev
This paper uses pleiotropy to discover new genetic loci for OSA and provide biological hypotheses by combining colocalization tests with pleiotropy analysis.
PLoS Genetics · Dec 27, 2022Peer-reviewedGenetics