Author

Seila De Leon

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Antònia Obrador‐HeviaiD· 1 shared Chinedu I. UkaegbuiD· 1 shared Cristina AlendaiD· 1 shared Elena M. StoffeliD· 1 shared Inmaculada SalcesiD· 1 shared Joann Balazs SweasyiD· 1 shared Joanna A. GibsoniD· 1 shared José ReyesiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Antònia Obrador‐HeviaORCID

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1 paper

Recent·Most cited

Mutational signature profiling classifies subtypes of clinically different mismatch repair deficient tumors with a differential immunogenic response potential

Mar Giner-Calabuig, Seila De Leon, Julian Wang, Tara D. Fehlmann, Chinedu I. Ukaegbu, Joanna A. Gibson, Miren Alustiza, María Dolores Picó, Cristina Alenda, Maite Herráiz, Marta Carrillo Palau, Inmaculada Salces, José Reyes, Silvia P. Ortega, Antònia Obrador‐Hevia, , Rosa M. Xicola

This study classifies MMR-deficient tumors into subtypes based on mutational signatures and immunogenic potential, revealing clinical and molecular differences.

bioRxiv · Sep 28, 2021 · PreprintGenomics