Quantitative analysis of the frequency of chromosome loss following DSB induction
Seiya Matsuno, Ryo Ishida, Ryotaro Kawasumi, Kouji Hirota, Takuya Abe
This study quantifies how DNA damage, specifically DSBs and nicks, leads to chromosome loss in minichromosomes, contributing to aneuploidy.
bioRxiv · Jan 15, 2025 · PreprintMolecular Biology