A DISEASE MODEL FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) WITH MUTATIONS IN TP53 AND ITS APPLICATION FOR DRUG REPURPOSING.
Anton Yuryev, Anastasia P. Nesterova, Sergey Sozin, Maria Shkrob
The paper develops an in silico disease model for DIPG with TP53 and H3K27M mutations to identify potential drugs for repurposing.
medRxiv · Jun 22, 2022 · PreprintGenetic & Genomic Medicine