A Multi-Organ Single-Cell Atlas Maps Allergen and Organ-Specific Cellular Dynamics in the Progression from Food Allergy to Anaphylactic Shock
Richard L. Jayaraj, Xue Xia, Mahmoud Al-Azab, Yiyiao Liang, Sohaib H. Mazhar, Seth L. Alpert, Saima Khan, Amina Nazir, Jiawen Xu, C. Li, Bing Huang, Mourad Aribi, Xin Li, Abdelouahab Bellou
This paper constructs a multi-organ single-cell atlas to map cellular dynamics during food allergy progression to anaphylactic shock in mice, identifying organ-specific pathologies and conserved inflammatory pathways.
bioRxiv · Feb 7, 2026 · PreprintImmunology