Detrimental Influence of Arginase-1 in Infiltrating Macrophages on Post-Stroke Functional Recovery and Inflammatory Milieu
Hyung Soon Kim, Seung Ah Jee, Ariandokht Einisadr, Yeojin Seo, Hyo Gyeong Seo, Byeong Seong Jang, Hee Hwan Park, Won‐Suk Chung, Byung Gon Kim
This study shows that Arg1 in macrophages impairs post-stroke recovery by promoting fibrosis and inflammation, and its removal improves motor function and synaptic density.
Proceedings of the National Academy of Sciences · Feb 14, 2025Peer-reviewedNeuroscience