Author

Seung-won Choi

Columbia University

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Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

David A. KnowlesiD· 1 shared Haochen YangiD· 1 shared Jiahao JiangiD· 1 shared Jiayu SuiD· 1 shared Megan D. SchertzeriD· 1 shared Qiliang Lai· 1 shared Raúl RabadániD· 1 shared Stella Park· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

David A. KnowlesORCID

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1 paper

Recent·Most cited

A computational framework for mapping isoform landscape and regulatory mechanisms from spatial transcriptomics data

Jiayu Su, Yiming Qu, Megan D. Schertzer, Haochen Yang, Jiahao Jiang, Tenzin W. Lhakhang, Theodore M. Nelson, Stella Park, Qiliang Lai, Xi Fu, Seung-won Choi, David A. Knowles, Raúl Rabadán

This paper introduces SPLISOSM, a framework for analyzing spatial transcriptomics data to detect isoform-level patterns, identifying spatially variable transcript diversity and regulatory relationships in mouse and human brain tissues.

bioRxiv · May 2, 2025 · PreprintBioinformatics