Towards mechanistic models of mutational effects: Deep Learning on Alzheimer's Aβ peptide
Bo Wang, Shahab Razavi, Eric R. Gamazon
The paper uses deep learning to model mutational effects on Aβ42 peptide aggregation traits from DMS data, showing improved performance with geometric-structural features.
Computational and Structural Biotechnology Journal · Jan 1, 2023Peer-reviewedBioinformatics