Molecular mechanisms of immune evasion by host protein glycosylation of a bacterial immunogen used in nucleic acid vaccines
Mukaddes Sena Cinar, Trevor M. Adams, Fathima Zahra Nawaz, Elif S. Demir, Mariye Erol Demirturk, Aidan P. Keelaghan, Shaima Muhammed Nazaar, Blaine Russell Roberts, Ahmet Ozdilek, Fikri Y. Avci
This study identifies how host glycosylation of bacterial antigens in nucleic acid vaccines reduces immune recognition by shielding epitopes and altering antibody binding.
Journal of Biological Chemistry · Apr 3, 2026Peer-reviewedBiochemistry