Transcriptional activity of TRF2 is telomere length dependent
Ananda Kishore Mukherjee, Shalu Sharma, Parashar Dhapola, Dhurjhoti Saha, Tabish Hussain, Sumitabho Deb Roy, Gunjan Purohit, Anirban Kar, Ankita Singh, Suman Sengupta, Vivek Srivastava, Manish Kumar, Sagar Sengupta, Shantanu Chowdhury
The paper shows that longer telomeres reduce TRF2's extra-telomeric occupancy, including at the p21 promoter, making TRF2 a telomere-length-dependent repressor of p21.
bioRxiv · Jun 3, 2016 · PreprintMolecular Biology