A Transcriptionally Distinct Intermediate Activation State Precedes Langerhans Cell Migration from the Epidermis
Artem M. Kiselev, Axel D. Schmitter-Sánchez, Sudhanshu Mishra, Hyeri Kim, Sharod Williams, Sang‐Bum Park
This study identifies an intermediate activated state of Langerhans cells before migration using single-cell transcriptomics and intravital imaging, revealing complement signaling's role in their behavior during skin injury.
bioRxiv · May 29, 2025 · PreprintCell Biology