Artem M. Kiselev

A Transcriptionally Distinct Intermediate Activation State Precedes Langerhans Cell Migration from the Epidermis

This study identifies an intermediate activated state of Langerhans cells before migration using single-cell transcriptomics and intravital imaging, revealing complement signaling's role in their behavior during skin injury.

Self-organizing human heart assembloids with autologous and developmentally relevant cardiac neural crest-derived tissues

This paper develops a human heart assembloid model that recapitulates cardiac neural crest integration and reveals antidepressant effects on cardiac development.

Human heart assembloids with autologous tissue-resident macrophages recreate physiological immuno-cardiac interactions

This paper introduces hHMA, a human heart-macrophage assembloid model that integrates autologous cardiac macrophages with heart organoids to study immune-cardiac interactions and disease mechanisms.

Systematic dissection of biases in whole-exome and whole-genome sequencing reveals major determinants of coding sequence coverage

This study systematically evaluates coverage biases in whole-exome and whole-genome sequencing, finding that some WES platforms outperform others and that WES can match WGS in variant discovery.