Author

Shaylee Kieffer

Fred Hutch Cancer Center

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Molecular Biology· 1

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Approach:statistical model· 1

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Chloe Unterseher· 1 shared Hiroshi TsuchidaiD· 1 shared Richard O. AdeyemiiD· 1 shared Rosevalentine BosireiD· 1 shared Xuhui Jin· 1 shared

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2025-2025 · peak 1/yr

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Chloe Unterseher

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1 paper

Recent·Most cited

The BRCA1-RAD51 Axis Regulates SCAI/REV3 Dependent Replication Fork Maintenance

Chloe Unterseher, Hiroshi Tsuchida, Rosevalentine Bosire, Shaylee Kieffer, Xuhui Jin, Richard O. Adeyemi

The paper shows BRCA1 regulates RAD51 to maintain replication fork integrity via SCAI and REV3, leading to DNA breaks and genomic instability when these factors are absent.

bioRxiv · Nov 25, 2025 · PreprintMolecular Biology