Author

Hiroshi Tsuchida

Fred Hutch Cancer CenterORCID 0009-0002-1555-3698Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

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Approach:statistical model· 1

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Chloe Unterseher· 1 shared Richard O. AdeyemiiD· 1 shared Rosevalentine BosireiD· 1 shared Shaylee Kieffer· 1 shared Xuhui Jin· 1 shared

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1 shared paperMolecular Biology

Chloe Unterseher

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1 paper

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Molecular BiologybioRxivPreprintNov 25, 2025

The BRCA1-RAD51 Axis Regulates SCAI/REV3 Dependent Replication Fork Maintenance

Chloe Unterseher, Hiroshi Tsuchida, Rosevalentine Bosire…·Richard O. Adeyemi

The paper shows BRCA1 regulates RAD51 to maintain replication fork integrity via SCAI and REV3, leading to DNA breaks and genomic instability when these factors are absent.

DOI 10.1101/2025.11.25.689574

statistical model

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